Liver Tissue Examination of Mice Using 10% BNF Fixation For 6 Hours And 16 Hours

The fixation process is the first stage in manufacture of histopathological preparations which aims to preserve tissue and harden tissue, so that be observed does not change shape or size. BNF solution (Neutral Buffer Formalin) 10% has been used as a routine fixative It gold standard histology laboratories for decades. material this study was because it easier use can long period time. This determine differences microscopic results liver mice (Mus musculus) fixed with 6 hours 16 hours. type research descriptive analytic. carried out at Barokah Laboratory/ dr.Mezfi Unita on 04-05 March 2022 total sample 20 samples musculus). showed average were good. conclusion from there no difference using Hematorylin-Eosin staining. time an alternative examination short term term.